Sunday, February 10, 2013

Anti-gay religious group gets funding from Canadian government to work in Africa

OTTAWA - An evangelical organization that describes homosexuality as a "perversion" and a "sin" is receiving funding from the Government of Canada for its work in Uganda, where gays and lesbians face severe threats.

The federal government has denounced virulent homophobia in that East African country and Foreign Affairs Minister John Baird has condemned plans for an anti-gay bill that could potentially include the death penalty for homosexuals.

At the same time the government is providing $544,813 in funding for Crossroads Christian Communications ? an Ontario-based evangelical group that produces television programming ? to help dig wells, build latrines and promote hygiene awareness in Uganda through 2014.

Until Tuesday, the organization's website carried a list of "sexual sins" deemed to be "perversion": "Turning from the true and/or proper purpose of sexual intercourse; misusing or abusing it, such as in pedophilia, homosexuality and lesbianism, sadism, masochism, transvestism, and bestiality."

Lower down the page, the group asks sinners to "repent."

"God cares too much for you (and all of His children) to leave such tampering and spiritual abuse unpunished," according to the group's website.

Just hours after The Canadian Press contacted the group to ask a spokesperson about the site, the page in question disappeared from public view.

The organization is being funded by the Canadian International Development Agency. Just a few days ago the Quebec government announced its desire to create its own parallel agency because it no longer supported CIDA's policy choices.

This particular funding choice may also conflict with the federal government's own statements.

Last October, Baird denounced abuses against gays and lesbians and specifically singled out Uganda in a speech at an international conference in Quebec City.

"We will speak out on the issues that matter to Canadians ? whether it is the role and treatment of women around the world, or the persecution of gays," Baird told the Inter-Parliamentary Union conference.

"Canada will speak out."

In that speech, Baird shared the story of a Ugandan gay-rights advocate who was bludgeoned to death in his own home.

That speech provoked an angry reaction from the head of the Ugandan delegation, Rebecca Kadaga, who accused Baird of "arrogance" and "ignorance" and demanded an apology.

Crossroads defends its position on homosexuality as grounded in scripture.

"Crossroads' views on sexuality are informed by our Christian faith and values," spokeswoman Carolyn Innis told The Canadian Press in an email.

She said the projects funded by CIDA do not include evangelical work and are focused on specific objectives.

On the group's website, under the section "Who We Are," the group describes its mission the following way ? "Our motivation: To communicate a visible expression of God's love, and contribute to the transformation of lives around the world."

But that doesn't mean the group is getting involved in Uganda's homosexuality debate, Innis said.

"It has not been a practice of Crossroads to influence matters of policy in countries in which we are completing relief or development projects," she said.

Steve Foster, president of the Quebec LGBT Council, said the federal government should stop funding groups like Crossroads.

"It's unacceptable that the government would accept that kind of organization as an international-co-operation organization," Foster said.

"Taxpayers' money should not be used to finance religious groups working abroad, who furthermore contribute to the creation of discriminatory ? even inhumane and dangerous ? policy."

Foster calls it a "dangerous" shift from the government toward using religious groups to perform international development work.

He's not alone to perceive a trend.

A study by the Canadian Research Institute on Humanitarian Crisis and Aid concluded that, between 2005 and 2010, the funding for religious non-government organizations increased 42 per cent. Secular groups saw an increase of five per cent.

Prime Minister Stephen Harper has been asked about that disparity.

"We consider the efficiency of projects,'' Harper replied during a Montreal news conference last month. ''(We) do not consider the religion of groups promoting these projects."

As for Crossroads' opinion on homosexuality, the government sought to keep its distance.

"Our government does not endorse these particular views," Rick Roth, a Baird spokesman, said in an email.

"Canada's views are clear ? we have been strongly opposed to the criminalization of homosexuality or violence against people on the basis of their sexual orientation."

The minister responsible for CIDA, Julian Fantino, has also said funding is doled out "on merit."

A CIDA spokeswoman, Amy Mills, added in an email: "Canada's views are clear ? we have been strongly opposed to the criminalization of homosexuality or violence against people on the basis of their sexual orientation."

She offered no comment on Crossroads' views on homosexuality.

An anti-gay bill was returned to the order paper for debate in Uganda's parliament last week. The MP who tabled it has spoken of replacing the death penalty with prison sentences, but it's unclear what the final version of the legislation might look like.

Source: http://news.yahoo.com/anti-gay-religious-group-gets-funding-canadian-government-185228049.html

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Saturday, February 9, 2013

Colon cancer exhibits a corresponding epigenetic pattern in mice and humans

Friday, February 8, 2013

Tumourigenesis is driven by genetic alterations and by changes in the epigenome, for instance by the addition of methyl groups to cytosine bases in the DNA. A deeper understanding of the interaction between the genetic and epigenetic mechanisms is critical for the selection of tumour biomarkers and for the future development of therapies. Human tumour specimens and cell lines however contain a plethora of genetic and epigenetic changes, which complicate data analysis. In contrast, certain mouse tumour models contain only a single genetic mutation and allow the analysis of nascent tumours. Scientists of the Max Planck Institute for Molecular Genetics in Berlin have now discovered a recurring pattern of more than 13,000 epigenetic alterations in young tumours of the mouse. This genome-wide pattern was found to be partly conserved in human colon carcinoma, and may therefor facilitate the identification of novel clinical colon cancer biomarkers for early detection.

Two kinds of molecular changes are known to trigger tumour development: one is genetic mutations ? i.e. alterations in the alphabetic sequence of the DNA ?activating genes that lead to uncontrolled growth of tumours, or inactivating genes that inhibit this growth. The other is epigenetic modifications, for example new distributions of methyl groups in the DNA that contribute to the genetic information in the cancer cells being interpreted differently.

Genetic and epigenetic mechanisms work together in cancer development ? but little was known about how these systems mutually influence one another, and which changes first come to light. These questions can only be answered with great difficulty through investigating human tumours: the cancer is usually already several years old when diagnosed. Accordingly, the cancer cells already exhibit thousands of genetic and epigenetic changes at this stage, which complicates the analysis.

The matter is different for the corresponding polyps in mice, which the researchers can investigate considerably earlier following their formation. For this reason, scientists of the Max Planck Institute for Molecular Genetics have now pursued the question of which epigenetic changes in intestinal tumours occur first with the help of a mouse model.

"With mice, we can investigate the first changes much more easily than with humans", says Markus Morkel, who led the study. The scientists analysed the epigenetic changes in a strain of mice with a defective copy of the APC gene. This gene serves as an intestinal tumour suppressor in mice as well as in humans. Accordingly, it has lost its functionality in a majority of patients with colon cancer.

The results displayed a clear picture:The researchers recognised a recurring pattern of more than 13,000 epigenetic changes in all of the mouse tumour samples. By contrast, they did not find this pattern in healthy intestine or in intestinal stem cells, which are the cells of origin of the tumour. Since the mice ?and hence the tumours? were less than three months old, the changes must have already spread shortly after the first genetic mutation in the APC gene within the tumour cells. According to the scientists, the first mutation already leads to pathological activation of numerous enzymes controlling the epigenetic mechanisms.

Remarkably, the molecular biologists discovered large parts of the tumour-specific epigenetic pattern not only in the mouse, but also in human colon cancer tissue. "These initial epigenetic changes could therefore serve as markers and significantly simplify the early diagnosis of colon tumours in the future", hopes Markus Morkel. Patients would merely have to provide a blood sample for the diagnosis and could forego an enteroscopic procedure.

###

Max-Planck-Gesellschaft: http://www.mpg.de

Thanks to Max-Planck-Gesellschaft for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/126705/Colon_cancer_exhibits_a_corresponding_epigenetic_pattern_in_mice_and_humans

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Science Studio update - and a new challenge

The other day I gave you a quick update on various projects and events, including the update on Science Studio ? the multimedia version of Open Laboratory project. With eight days to go, our Kickstarter project is only $500 shy of the $5000 we need to get the podcasting project funded. As the response from the community was so strong, Rose, Ben and I thought we could do more ? include video if we can crack $8000. Do you think we can do it? I bet we can, but we rely on you, and your ability and willingness to spread the word. Here is what Rose says:

Oh man, people, you are awesome. We?re so close to our goal I can taste all the amazing audio we?ll be bringing you. It kind of tastes like electricity.

But you know what, we?ve still got eight days left. And Ben, Bora and I want to make this the best thing we possibly can, so we?ve decided to up the ante a little bit. Right now, we?re focusing on audio. And, like we said, there?s a ton of that. But there?s all sorts of other stuff out there too, video, animations, graphics, interactives, maps, the list goes on. We didn?t think we?d be able to do it all, but if we get a little more of your help, we can chip away at that giant pile of amazing content.

So here?s the challenge. If we can crack $8,000, we?ll add video to the mix. That?s right, from Minute Physics to TED Ed to Vsauce to Instant Egghead to Creature Cast to Vi Hart. We know you love video, and we love it too. Let?s make this happen together, everybody.

What do you say? Are you up for the challenge? Let?s play.

Source: http://rss.sciam.com/click.phdo?i=649680e92168404ad2f853130ddad58f

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Deerfield's Christine Stitcher Advances to Gymnastics State Finals ...

Deerfield High School gymnast Christine Stitcher is heading to the state finals.

Stitcher qualified at Thursday's section meet to advance on the vault and bars, as well as in the all-around competition, according to Warriors Coach?Carol Myers. This is her third trip to the state finals.

"Christine struggled in the first half of the meet, falling off the beam and some minor mishaps on floor, but really came through on vault and bars," Myers said.?

Myers pointed out some other notable performances.

"Leslie Ross hit her season high of 8.225 on bars," Myers said. "And Ally Perbohner participated in all four events giving her tremendous experience to help her lead the team next year when Christine is gone. Freshman Emily Berlin, unfortunately could not perform on beam because she sprained her MCL during regional floor." ?

The finals take place next weekend at Palatine High School.

Christine had a request of Deerfield Patch, which we were happy to oblige, and asked that we include this question at the end of the story:

"Ben Weiss, will you go to turnabout with Christine?"

For more Warrior sports news, sign up for our free newsletter.

Source: http://deerfield.patch.com/articles/deerfield-s-christine-stitcher-advances-to-gymnastics-finals

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Waiting for the Reckoning (talking-points-memo)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories News, News Feeds and News via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/283626183?client_source=feed&format=rss

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Friday, February 8, 2013

Wall St extends losses; Nasdaq off 1 pct

NEW YORK (Reuters) - U.S. stocks fell further on Thursday, with the Nasdaq falling 1 percent, as a sharp drop in the euro against the safe-haven dollar and yen curbed investors' appetite for risky assets.

The Dow Jones industrial average was down 119.84 points, or 0.86 percent, at 13,866.68. The Standard & Poor's 500 Index was down 12.31 points, or 0.81 percent, at 1,499.81. The Nasdaq Composite Index was down 30.76 points, or 0.97 percent, at 3,137.72.

(Reporting By Angela Moon; Editing by Kenneth Barry)

Source: http://news.yahoo.com/wall-st-extends-losses-nasdaq-off-1-pct-161205993--finance.html

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Lawmakers consider regulating drone strikes

Senate Intelligence Committee Chair Sen. Dianne Feinstein, D-Calif., right, welcomes CIA Director nominee John Brennan on Capitol Hill in Washington, Thursday, Feb. 7, 2013, prior to the start of Brennan's confirmation hearing before the committee. (AP Photo/J. Scott Applewhite)

Senate Intelligence Committee Chair Sen. Dianne Feinstein, D-Calif., right, welcomes CIA Director nominee John Brennan on Capitol Hill in Washington, Thursday, Feb. 7, 2013, prior to the start of Brennan's confirmation hearing before the committee. (AP Photo/J. Scott Applewhite)

CIA Director nominee John Brennan testifies on Capitol Hill in Washington, Thursday, Feb. 7, 2013, during his confirmation hearing before the Senate Intelligence Committee. (AP Photo/Manuel Balce Ceneta)

CIA Director nominee John Brennan testifies on Capitol Hill in Washington, Thursday, Feb. 7, 2013, during his confirmation hearing before the Senate Intelligence Committee. (AP Photo/Manuel Balce Ceneta)

CIA Director nominee John Brennan, testifies before a Senate Select Intelligence Committee confirmation hearing in Washington, Thursday, Feb. 7, 2013. (AP Photo/Manuel Balce Ceneta)

CODEPINK co-founder Medea Benjamin, right and other CODEPINK protestors, a group opposed to U.S. militarism, disrupt the start of the Senate Intelligence Committee confirmation hearing for John Brennan, Thursday, Feb. 7, 2013, on Capitol Hill in Washington. (AP Photo/J. Scott Applewhite)

(AP) ? CIA Director-designate John Brennan's vigorous defense of drone strikes to kill terror suspects ? even American citizens ? overseas is causing key lawmakers to consider lifting secrecy from what has become an important weapon in the fight against al-Qaida.

Brennan, President Barack Obama's top counterterror adviser, was grilled for more than three hours Thursday before the Senate Intelligence Committee on the drone program he leads, as well as on the CIA's harsh interrogation techniques during the Bush administration, which he denounced, and on leaks of classified information to the media, which Brennan vehemently denied being a part of.

Despite Brennan's wide-ranging testimony and the White House's release of a top secret memo explaining its legal rationale for the strikes just hours before the confirmation hearing began, some senators afterward said it was time to bring the drone program into the open.

In a hearing that was interrupted by anti-drone protests that brought it to a brief halt at the outset, Brennan told the committee that missile strikes by the unmanned drones are used only against targets planning to carry out attacks against the United States, never as retribution for an earlier one.

"Nothing could be further from the truth," he declared.

Referring to one American citizen killed by a drone in Yemen in 2011, he said Anwar al-Awlaki had ties to at least three attacks planned or carried out on U.S. soil. They included the Fort Hood, Texas, shooting that claimed 13 lives in 2009, a failed attempt to down a Detroit-bound airliner the same year and a thwarted plot to bomb cargo planes in 2010.

"He was intimately involved in activities to kill innocent men women and children, mostly Americans," Brennan said.

The committee's chairwoman, Sen. Dianne Feinstein, D-Calif., told reporters after the hearing that she wanted to open more of the program to the public so U.S. officials can acknowledge the strikes and correct what she said were exaggerated reports of civilian casualties.

Feinstein said she and other senators were considering legislation to set up a special court system to regulate drone strikes, similar to the one that signs off on government surveillance in espionage and terrorism cases.

Speaking with uncharacteristic openness about the classified program, Feinstein said that the CIA had allowed her staff to make more than 30 visits to the agency's northern Virginia headquarters to monitor strikes but that such transparency needed to be increased. Her comments came after the White House, under pressure from the committee, gave senators on the panel a Justice Department memo outlining the legal justification for drone strikes. But senators complained that their staff wasn't allowed to see it.

"I think the process set up internally is a solid process," Feinstein said of the methods used to decide when to launch drones and against whom, but added: "I think there's an absence of knowing exactly who is responsible for what decision. So I think we need to look at this whole process and figure a way to make it transparent and identifiable."

Rep. Adam Schiff, D-Calif., a member of the House Intelligence Committee, said his panel also had been looking at establishing a "court-like entity" to review the strikes.

"I think the House and Senate ought to put their heads together and come up with some way to require either initially or after the fact, a review of an operation when it takes the life of an American citizen," Schiff said.

In a long afternoon in the witness chair, Brennan was questioned on other issues, such as the use of waterboarding and other interrogation techniques in the George W. Bush administration. He declined to say whether he believes waterboarding, which simulates drowning, amounted to torture, but he said firmly it was "something that is reprehensible and should never be done again."

Brennan, 57, is a veteran of more than three decades in intelligence work. He withdrew his name from nomination to head the CIA four years ago amid questions about the role he played at the CIA when the Bush administration approved waterboarding and other forms of "enhanced interrogation" of suspected terrorists.

On the question of waterboarding, Brennan said that while serving as a deputy manager at the CIA during the Bush administration, he was told such interrogation methods produced "valuable information." Now, after reading a 300-page summary of a 6,000-page report on CIA interrogation and detention policies, he said he does "not know what the truth is."

Brennan bristled once during the day, when he was questioned about leaks to the media about an al-Qaida plot to detonate a new type of underwear bomb on a Western airline.

Sen. James Risch, R-Idaho, accused him of having leaked classified information in a telephone call with former government officials who were preparing to make television appearances to explain the plot.

"I disagree with that vehemently," the nominee shot back.

On May 7 of last year, The Associated Press reported that the CIA thwarted an ambitious plot by al-Qaida's affiliate in Yemen to destroy a U.S.-bound airliner, using a bomb with a sophisticated new design. The bombing would have taken place near the anniversary of the killing by U.S. Navy SEALs of Osama bin Laden. The next day, The New York Times and the Los Angeles Times reported that the would-be bomber was cooperating with U.S. authorities.

Risch and Sen. Dan Coats of Indiana were among those who contended Brennan inadvertently had revealed that the U.S. had a spy inside Yemen's al-Qaida branch when, hours after the first AP report appeared, he told a group of media consultants that "there was no active threat during the bin Laden anniversary because ... we had inside control of the plot."

Brennan won praise from several members of the committee as the day's proceedings drew to a close.

"I think you're the guy for the job, and the only guy for the job," said Sen. Jay Rockefeller, D-W.Va.

The panel will meet in closed session next week to discuss classified material.

___

Associated Press writers Julie Pace, Lara Jakes, Donna Cassata and David Espo contributed to this report.

___

Follow Kimberly Dozier on Twitter: http://twitter.com/KimberlyDozier

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2013-02-08-Brennan-CIA/id-bf944b96b1fb43478a9b1e7d8121b0c5

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